204870-M

Complement C3d, Human

Name: Complement C3d, Human
Brand: MM

Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.

Synonym(s):

Complement Protein

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About This Item

UNSPSC Code:

12352202

Key Documents

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Quality Level

100

assay

≥85% (SDS-PAGE)

form

liquid

does not contain

preservative

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

impurities

IgG, IgM, IgA, C5, Factor H, Factor I, trace

storage temp.

−70°C

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This Item	204860	204881	204863
204870-M Complement C3d, Human	204860 Complement C3b, Human	204881 Complement C3a, Human	204863 Complement iC3b, Human
assay ≥85% (SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay ≥90% (SDS-PAGE)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
form liquid	form liquid	form liquid	form liquid
impurities IgG, IgM, IgA, C5, Factor H, Factor I, trace	impurities IgG, IgA, IgM, C5, Factor H, or Factor I, trace	impurities ≤10% C3adesArg	impurities IgG, IgA, IgM, C5, Factor H, or Factor I, trace
storage condition OK to freeze, avoid repeated freeze/thaw cycles	storage condition OK to freeze, avoid repeated freeze/thaw cycles	storage condition OK to freeze, avoid repeated freeze/thaw cycles	storage condition OK to freeze, avoid repeated freeze/thaw cycles
storage temp. −70°C	storage temp. −70°C	storage temp. −70°C	storage temp. −70°C

General description

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS, pH 7.2.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol.153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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