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218755

Sigma-Aldrich

Caspase-4 Inhibitor I

The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):
Caspase-4 Inhibitor I, Ac-LEVD-CHO
Empirical Formula (Hill Notation):
C22H36N4O9
CAS Number:
Molecular Weight:
500.54

Quality Level

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

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235420400010218826
Caspase-4 Inhibitor I The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

218755

Caspase-4 Inhibitor I

Caspase-3 Inhibitor I The Caspase-3 Inhibitor I, also referenced under CAS 169332-60-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

235420

Caspase-3 Inhibitor I

Caspase-1 Inhibitor I The Caspase-1 Inhibitor I, also referenced under CAS 143313-51-3, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

400010

Caspase-1 Inhibitor I

assay

≥95% (HPLC)

assay

≥90% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

form

lyophilized solid

form

solid

form

powder

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

color

white

color

white

color

white

color

yellow

solubility

water: 1 mg/mL

solubility

DMSO: 5 mg/mL, water: soluble

solubility

DMSO: 5 mg/mL, water: soluble

solubility

methanol: 10 mg/mL, DMSO: 200 mg/mL

General description

A reversible caspase-4 (ICH-2) inhibitor.
A reversible caspase-4 inhibitor.

Biochem/physiol Actions

Cell permeable: no
Primary Target
caspase-4
Product does not compete with ATP.
Reversible: yes

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Leu-Glu-Val-Asp-CHO

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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