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230734

Chorionic Gonadotropin, Human Urine, Standard Grade

Chorionic Gonadotropin, Human Urine, Standard Grade, CAS 9002-61-3, is a native glycoprotein hormone that is synthesized by chorionic tissue of the placenta and found in urine during pregnancy.

Synonym(s):

Chorionic Gonadotropin, Human Urine, Standard Grade, hCG

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77
Biological source:
human
Form:
solid

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biological source

human

Quality Level

description

Merck USA index - 14, 2216
Protein Concentration/ Report Result, weight

sterility

non-sterile

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

pI 

4.9

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

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This Item
869031-M1297001C8554
biological source

human

biological source

human

biological source

-

biological source

human urine

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

form

solid

form

solid

form

-

form

lyophilized powder

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

-

storage condition

-

solubility

water: soluble

solubility

water: soluble

solubility

-

solubility

H2O: 1 mL/vial, saline: 1 mL/vial

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

Native, human chorionic gonadotropin from urine. Glycoprotein hormone synthesized by chorionic tissue of the placenta and found in urine during pregnancy. Also present in body fluids of patients with trophoblastic disease and ovarian tumors. ≥3000 IU/mg (Who 3rd IS 75/537).

Biochem/physiol Actions

≥3000 IU/mg solids (Who 3rd IS 75/537)

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of reconstituted solutions. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chandy, K.G., et al. 1990. Science247, 973.
Smith, D.B. and Johnson, K.S. 1988. Gene67, 31.
Tempel, B.L., et al. 1988. Nature332, 837.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Carcinogenic / Teratogenic (D)

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kimberly Mitchell et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(23), 12772-12783 (2020-05-30)
The luteinizing hormone surge is essential for fertility as it triggers ovulation in females and sperm release in males. We previously reported that secretoneurin-a, a neuropeptide derived from the processing of secretogranin-2a (Scg2a), stimulates luteinizing hormone release, suggesting a role
Xuzhe Zhang et al.
Molecular biology and evolution, 37(2), 507-523 (2019-10-22)
Evolution of highly invasive placentation in the stem lineage of eutherians and subsequent extension of pregnancy set eutherians apart from other mammals, that is, marsupials with short-lived placentas, and oviparous monotremes. Recent studies suggest that eutherian implantation evolved from marsupial
Elisabet Rosàs-Canyelles et al.
Science advances, 6(17), eaay1751-eaay1751 (2020-06-05)
The process by which a zygote develops from a single cell into a multicellular organism is poorly understood. Advances are hindered by detection specificity and sensitivity limitations of single-cell protein tools and by challenges in integrating multimodal data. We introduce

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Questions

  1. Hi, we would like to double-check a couple of things: the sample is from human urine (not recombinant). How many mg of protein are present? We ordered 2.5 mg, so 7500 IU. 1l unit =2.35×10−12 moles, or 6×10−8 gram; so 450 ugs correct? Thanks

    1 answer
    1. This product is from human urine. The protein concentration can be found on the lot specific Certificate of Analysis. A Certificate can be accessed in the link below:
      https://www.sigmaaldrich.com/product/mm/230734#product-documentation

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