233490

Coagulation Factor XII, Human Plasma

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.

• Synonym(s): Coagulation Factor XII, Human Plasma
• CAS Number: 9001-30-3
• MDL number: MFCD00285653
• UNSPSC Code: 12352202
• NACRES: NA.42

Properties

• Quality Level: 100
• description: Merck USA index - 14, 3925
• form: liquid
• specific activity: ≥20 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.

Native coagulation factor XII from human plasma. A single-chain polypeptide, which once activated (principally from the action of kallikrein) is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Analysis Note

single band by SDS-PAGE

Other Notes

Specific activity is measured by clotting assay and compared to a standard curve produced using normal pooled human plasma.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable