236608-M
C-Reactive Protein, Human, Recombinant, E. coli
C-Reactive Protein, Human, Recombinant, E. coli, CAS 9007-41-4, is suitable for immunological studies.
Synonym(s):
C-Reactive Protein, Human, Recombinant, E. coli, rhCRP
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About This Item
Recommended Products
recombinant
expressed in E. coli
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
solubility
aqueous buffer: soluble
storage temp.
2-8°C
General description
M.W. 23,000 (monomer); 115,000 (pentamer).
Recombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.
Recombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera.Calibrated by electroimmunoassay against WHO reference standard or equivalent.
Warning
Toxicity: Standard Handling (A)
Physical form
In 140 mM NaCl, 20 mM Tris-HCl, 2 mM CaCl₂, 0.05% NaN₃, pH 7.5.
Other Notes
Paffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol.24, 975.
Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.
Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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