This material has a published relative density of 1.05-1.06 g/mL. The density value reported in the product SDS is 1.05 g/mL.
238470
Cremophor® EL
Synonym(s):
Castor oil polyoxyethylene ether, Ethoxylated castor oil, PEG-35 castor oil, Polyoxyl 35 castor oil, polyoxyl 35 castor oil
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1 SET
$302.00
About This Item
form
liquid
Quality Level
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
clear pale yellow
CMC
~0.02%
solubility
ethanol: soluble
water: soluble, clear (at higher temperatures the solution will be come turbid)
density
1,050 g/cm3
application(s)
(Excipient in drug)
shipped in
ambient
storage temp.
2-8°C
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
1 of 4
This Item | C5135 | 30906 | 1547200 |
|---|---|---|---|
| form liquid | form liquid | form paste | form - |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
| solubility ethanol: soluble, water: soluble, clear (at higher temperatures the solution will be come turbid) | solubility - | solubility - | solubility - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level - |
| CMC ~0.02% | CMC - | CMC - | CMC - |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename USP |
General description
1 Set = 5 X 25 GM
A mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide in a molar ratio of 1 : 35, that acts as a nonionic surfactant and serves as a formulation vehicle (p.o. and i.v. administration) for poorly-water soluble pharmacological agents.
Hydrophilic-lipophilic balance (HLB) ~ 12 - 14.
Application
- Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.: This research examines the proteomic responses in Mongolian gerbils administered with carotenoids and retinol. Cremophor® EL is utilized as a solubilizing agent for these compounds, highlighting its role in biochemical studies involving lipid-soluble substances (Bohn et al., 2018).
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Other Notes
Gelderblom, H., et al. 2001. Eur. J. Cancer37, 1590.
Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.
Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cremophor is a registered trademark of BASF SE
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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What is the density of this product?
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What is the molecular weight of this product?
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The product is heterogenous and is mainly an ethoxylated triglyceride. However, there other ethoxylated compounds, such as ethoxylated fatty acids, are present. Based on the saponification number, this material has an estimated molecular weight of 2500 g/mol.
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Is this product sterile?
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This product is not sterile.
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