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264101

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Deoxycholic Acid sodium

An ionic detergent for the solubilization of membrane-bound proteins.

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Synonym(s):
Sodium deoxycholate, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4
CAS Number:
Molecular Weight:
414.55
Beilstein:
3581950
MDL number:

Quality Level

Assay

≥96% (TLC)

form

powder

mol wt

micellar avg mol wt 1200-5000
micellar wt 1700-4200

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

aggregation number

3-12
4 - 10

color

white to off-white

pKa 

6.2

CMC

2-6 mM (20-25°C)
4 - 8 mM

solubility

H2O: 2%, clear, colorless

cation traces

heavy metals: ≤20.0 ppm

HLB

16

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

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This Item
D6750SRE0046264103
Deoxycholic Acid sodium An ionic detergent for the solubilization of membrane-bound proteins.

Millipore

264101

Deoxycholic Acid sodium

Sodium deoxycholate ≥97% (titration)

Sigma-Aldrich

D6750

Sodium deoxycholate

Sodium deoxycholate Suitable for manufacturing of diagnostic kits and reagents

Sigma-Aldrich

SRE0046

Sodium deoxycholate

Sodium deoxycholate ULTROL® Grade, ≥99% (TLC), detergent to solubilize membrane-bound proteins in their native state

Millipore

264103

Sodium deoxycholate

form

powder

form

powder

form

-

form

solid

mol wt

micellar avg mol wt 1200-5000, micellar wt 1700-4200

mol wt

micellar avg mol wt 1200-5000

mol wt

micellar avg mol wt 1200-5000

mol wt

micellar avg mol wt 1200-5000, micellar wt 1200-4900

aggregation number

3-12, 4 - 10

aggregation number

3-12

aggregation number

3-12

aggregation number

3 - 12, 3-12

CMC

2-6 mM (20-25°C), 4 - 8 mM

CMC

2-6 mM (20-25°C)

CMC

2-6 mM (20-25°C)

CMC

2 - 6 mM, 2-6 mM (20-25°C)

solubility

H2O: 2%, clear, colorless

solubility

water: 50 mg/mL, clear, colorless to light yellow

solubility

-

solubility

-

General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.

Warning

Toxicity: Harmful (C)

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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