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Sigma-Aldrich

NG,NG′-Dimethyl-L-arginine, Dihydrochloride

Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

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Synonym(s):
NG,NG′-Dimethyl-L-arginine, Dihydrochloride, SDMA, 2HCl
Empirical Formula (Hill Notation):
C8H18N4O2 · 2HCl
Molecular Weight:
275.18

Quality Level

Assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to light yellow

solubility

water: 50 mg/mL

shipped in

wet ice

storage temp.

2-8°C

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This Item
09-814311203475886
form

solid

form

-

form

amorphous solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

-

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic)

color

white to light yellow

color

-

color

white

color

white

solubility

water: 50 mg/mL

solubility

-

solubility

water: 50 mg/mL

solubility

water: 50 mg/mL, methanol: soluble

General description

A cell-permeable endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
NOS in vitro
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Other Notes

Nam, S.W., et al. 1998. Arch. Pharm. Res. 21, 128.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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