Solutions used to reconstitute this product should first be brought to 37°C. Once at 37°C, the solution can be added to the product, and this mixture should remain at 37°C until complete solubilization occurs. If disturbed before complete solubilization, the product will gel or precipitate and become unusable.
341573
Fibrinogen, Bovine Plasma
Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains mpre than 95% clottable protein.
Synonym(s):
Fibrinogen, Bovine Plasma, Coagulation Factor I
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description
Merck USA index - 14, 4071
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
sterile distilled water: soluble
shipped in
wet ice
Quality Level
1 of 4
This Item | 341576-M | 341578 | F4883 |
|---|---|---|---|
| form lyophilized | form lyophilized | form lyophilized | form powder |
| solubility sterile distilled water: soluble | solubility sterile distilled water: soluble | solubility water: 25 mg/mL | solubility 0.9% NaCl: soluble |
| shipped in wet ice | shipped in - | shipped in wet ice | shipped in - |
| storage condition OK to freeze | storage condition OK to freeze | storage condition OK to freeze | storage condition - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 300 |
General description
Do not disturb until the fibrinogen is completely solubilized.
Native fibrinogen from bovine plasma. A plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is elevated in pregnancy, after surgical trauma, and myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
Native fibrinogen from bovine plasma. An acute phase plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Contains ≥ 95% clottable proteins.
Physical form
Lyophilized from 20 mM sodium citrate-HCl, pH 7.4.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C) for long term storage or store at room temperature (20°C) for short term storage. Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -20°C.
Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized.
Analysis Note
homogeneous by SDS-PAGE.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
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Yiming Zheng et al.
Nature cell biology, 22(3), 297-309 (2020-02-19)
Non-centrosomal microtubule-organizing centres (ncMTOCs) have a variety of roles that are presumed to serve the diverse functions of the range of cell types in which they are found. ncMTOCs are diverse in their composition, subcellular localization and function. Here we
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How to dissolve this product? Heat to 37 degree or leave it in 4°？
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How to sterilize this product after dissolve before use?
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Product 341573 is a non-sterile reagent. Please use sterile purified water for dissolution. The solution for reconstituted fibrinogen should first be warmed to 37°C. Once it reaches 37°C, the solution can be added to the fibrinogen. The mixture should be kept at 37°C until the fibrinogen is completely dissolved. Dissolution takes time, and shock during the dissolution process can produce insoluble precipitates. Therefore, allow the solution to stand still during the dissolution process. Please follow the dissolution method described on the product page.
Product homepage: https://www.merckmillipore.com/HK/en/product/Fibrinogen-Bovine-Plasma,EMD_BIO-341573#documentation
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IS this product sterile?
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This item is not sterile.
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