344852

Fumonisin B₂, Fusarium moniliforme

Structural analog of Fumonisin B₁ that has higher cytotoxicity and specific binding to primary rat hepatocytes than fumonisin B₁.

• Synonym(s): Fumonisin B₂, Fusarium moniliforme, FB₂
• Empirical Formula (Hill Notation): C₃₄H₅₉NO₁₄
• CAS Number: 116355-84-1
• Molecular Weight: 705.83
• MDL number: MFCD00133350
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• description: RTECS - TZ8335000
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: off-white
• solubility: methanol: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: NC(C(O)CC(O)CCCCCCC(CC(OC(=O)CC(CC(=O)O)C(=O)O)C(OC(=O)CC(CC(=O)O)C(=O)O)C(CCCC)C)C)C
• InChI: 1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)
• InChI key: UXDPXZQHTDAXOZ-UHFFFAOYSA-N

Description

General description

Structural analog of Fumonisin B1 (Cat. No. 344850) that has higher cytotoxicity and specific binding to primary rat hepatocytes than fumonisin B₁. Is not metabolized by primary hepatocytes.

Structural analog of Fumonisin B₁ (Cat. No. 344850) that has higher cytotoxicity and specific binding to primary rat hepatocytes than fumonisin B₁. Not metabolized by primary hepatocytes.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Primary rat hepatocytes

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliqout and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Cawood, M.E., et al. 1994. Food Chem. Toxicol. 32, 627.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H351
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable