Native, glial fibrillary acidic protein purified from human brain. Marker of sclerotic plaques in brain and gliosed brain. Isolated from normal human brain. A component of astroglial intermediate filaments. Forms glial filaments in astrocytes in the central nervous system and in some Schwann cells in peripheral nerves.
Molecular Weight: 43,000-49,000
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from 16 mM Sodium Bicarbonate, pH 8.5.
Preparation Note
Prepared from tissues of individuals that have been shown by certified tests to be negative for HbsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Anderiva, M., et al. 2001. Glia35, 189. Masood, K., et al. 1993. J. Neurochem. 61, 160. Liem, R.K., and Hutchison, S.B. 1982. Biochemistry21, 3221. Dahl, D. 1973. Brain Res.57, 343.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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