385911

Sigma-Aldrich

Hyaluronic Acid Binding Protein, Bovine Nasal Cartilage, Biotinylated

storage conditions

-20C

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−20°C

General description

Affinity purified. Binds specifically and strongly to hyaluronic acid (≥ 2000 M.W.). Composed of two binding polypeptides, which are derived from N-terminal regions of the hyaluronic acid binding proteoglycan and linkage proteins. Useful for ELISA and histochemistry.
Affinity-purified. Binds specifically and strongly to hyaluronic acid (≥2000 M.W.). Composed of two binding polypeptides, which are derived from N-terminal regions of hyaluronic acid binding proteoglycan and linkage proteins. Useful for ELISA and histochemistry.
M.W. 70,000-80,000 and 40,000-45,000.

Packaging

50 μg in Glass bottle

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 0.1 M sodium bicarbonate solution, pH 8.3

Reconstitution

Reconstitute with 100 µl distilled H₂O.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Tammi, R., et al. 1998. J. Biol. Chem. 273, 28878.
Kohda, D., et al. 1996. Cell 86, 767.
Heinegard, D., and Hascall, V.C. 1974. J. Biol. Chem. 249, 4250.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Marie C Hasselluhn et al.
Cells, 9(1) (2019-12-28)
The KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) mouse model is frequently employed for preclinical therapeutic testing, in particular in regard to antistromal therapies. Here, we investigate the prognostic implications of histopathological features that may guide preclinical trial design. Pancreatic tumor tissue from n =...
Lilong Guo et al.
Journal of cardiovascular development and disease, 7(3) (2020-08-23)
β-catenin has been widely studied in many animal and organ systems across evolution, and gain or loss of function has been linked to a number of human diseases. Yet fundamental knowledge regarding its protein expression and localization remains poorly described....
Ying Wang et al.
eLife, 9 (2020-06-02)
Tissue-resident macrophages in the mammary gland are found in close association with epithelial structures and within the adipose stroma, and are important for mammary gland development and tissue homeostasis. Macrophages have been linked to ductal development in the virgin mammary...
Irina N Andreichenko et al.
International journal of molecular sciences, 20(24) (2019-12-19)
4-methylumbelliferone (4MU) is an inhibitor of hyaluronan deposition and an active substance of hymecromone, a choleretic and antispasmodic drug. 4MU reported to be anti-fibrotic in mouse models; however, precise mechanism of action still requires further investigation. Here we describe the...
Alyson Wolk et al.
Cells, 9(3) (2020-03-08)
Sorsby's fundus dystrophy (SFD) is an inherited blinding disorder caused by mutations in the tissue inhibitor of metalloproteinase-3 (TIMP3) gene. The SFD pathology of macular degeneration with subretinal deposits and choroidal neovascularization (CNV) closely resembles that of the more common...

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