39468-M

Tricine

ULTROL^® Grade, ≥99% (titration), zwitterionic buffer useful in pH range 7.4-8.8

• Synonym(s): Tricine, ULTROL^® Grade, N-[ tris(Hydroxymethyl)methyl]glycine, N-[tris(Hydroxymethyl)methyl]glycine
• Empirical Formula (Hill Notation): C₆H₁₃NO₅
• CAS Number: 5704-04-1
• Molecular Weight: 179.17
• MDL number: MFCD00004277
• UNSPSC Code: 12161705
• NACRES: NA.25

Properties

• description: Merck USA index - 14, 9651
• Quality Level: 100
• assay: ≥99% (titration)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• pKa (20 °C): 8.2
• solubility: water: 20%
• cation traces: heavy metals: ≤1 ppm
• storage temp.: 10-30°C
• SMILES string: [N+H2](C(CO)(CO)CO)CC(=O)[O-]
• InChI: 1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)
• InChI key: SEQKRHFRPICQDD-UHFFFAOYSA-N

Description

General description

A zwitterionic amino acid commonly useful in the pH range of 7.4-8.8. Has a pK_a 8.05 at 25°C.

A zwitterionic buffer useful in the pH range of 7.4-8.8. Has a pK_a 8.05 at 25°C.

Application

• Rational Design and Comparison of Novel (99m)Tc-Labeled FAPI Dimers for Visualization of Multiple Tumor Types.: This study focuses on the design and evaluation of novel radiolabeled compounds for imaging various tumor types. Tricine is used as a buffer component to stabilize the radioactive isotopes, enhancing the imaging quality for precise tumor localization (Meng et al., 2024).

Warning

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable