InSolution Jasplakinolide, Jaspis johnstoni - Calbiochem

InSolution Jasplakinolide, Jaspis johnstoni, CAS 102396-24-7, is a 1 mM solution of Jasplakinolide, Jaspis johnstoni in DMSO. Acts as a potent inducer of actin polymerization and stabilization.

InSolution Jasplakinolide, Jaspis johnstoni - Calbiochem
Empirical Formula (Hill Notation):
Molecular Weight:
Pricing and availability is not currently available.

storage conditions


Quality Level


≥90% (HPLC)



mfr. no.


storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

shipped in

wet ice

General description

A cell-permeable F-actin probe. This macrocyclic cyclodepsipeptide, isolated from the marine sponge Jaspis johnstoni, is a potent inducer of actin polymerization and stabilization in vitro. It competes with Phalloidin (Cat. No. 516640) for actin binding (Kd = 15 nM) and enhances apoptosis induced by interleukin 2 (IL-2) deprivation. Also displays fungicidal, insecticidal, and anticancer properties.


50 μg in Plastic ampoule
Packaged under inert gas

Biochem/physiol Actions

Primary Target
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Kd = 15 nM for actin binding


Toxicity: Harmful (C)

Physical form

A 1 mM (50 µg/71 µl) solution of Jasplakinolide, Jaspis johnstoni (Cat. No. 420107) in DMSO.


Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Rosado, J.A., et al. 2000. J. Biol. Chem.275, 7527.
Posey, S.C., and Bierer, B.E. 1999. J. Biol. Chem.274, 4259.
Senderowicz, A.M., et al. 1995. J. Natl. Cancer Inst.87, 46.
Bubb, M.R., et al. 1994. J. Biol. Chem.269, 14869.
Scott, V.R., et al. 1988. Antimicrob. Agents Chemother.32, 1154.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK Germany


Flash Point(F)

188.6 °F - (Dimethylsulfoxide)

Flash Point(C)

87 °C - (Dimethylsulfoxide)

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