420311

Kanamycin Sulfate, Streptomyces kanamyceticus

Name: Kanamycin Sulfate, <i>Streptomyces kanamyceticus</i>
Brand: MM

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms.

Synonym(s):

Kanamycin Sulfate, Streptomyces kanamyceticus, Kamycin

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₃₆N₄O₁₁ · xH₂SO₄

CAS Number:

25389-94-0

Molecular Weight:

484.50 (free base basis)

UNSPSC Code:

51281654

Key Documents

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Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white to off-white

solubility

water: 10 mg/mL

shipped in

ambient

Storage temp.

10-30°C

InChI

1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

InChI key

OOYGSFOGFJDDHP-KMCOLRRFSA-N

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Show Differences

1 of 4

This Item	K1377	K1637	K4000
420311 Kanamycin Sulfate, Streptomyces kanamyceticus	K1377 Kanamycin sulfate from Streptomyces kanamyceticus	K1637 Kanamycin sulfate from Streptomyces kanamyceticus	K4000 Kanamycin sulfate from Streptomyces kanamyceticus
form solid	form powder	form powder	form powder
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 200
manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename -
storage temp. 10-30°C	storage temp. -	storage temp. -	storage temp. -
solubility water: 10 mg/mL	solubility H₂O: 10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)	solubility H₂O: 10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)	solubility H₂O: 50 mg/mL, clear, colorless to faintly yellow
storage condition OK to freeze	storage condition -	storage condition -	storage condition -

General description

Contains more than 98% kanamycin A. An aminoglycoside antibiotic affective against gram-positive and gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.

Potency: ≥750 µg/mg

Biochem/physiol Actions

Primary Target
protein biosynthesis

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9295.
Cardon, G.H., et al. 1993. Plant J.3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother.6, 516.
Umezawa, S., et al. 1968. J. Antibiot.21, 367.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS08

signalword

Danger

hcodes

H360D

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

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