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| Size/SKU | Availability | Price |
|---|---|---|
25 μg | Check Cart for Availability | $713.00 |
About This Item
NACRES:
NA.77
UNSPSC Code:
12352202
Form:
solid
Assay:
≥90% (SDS-PAGE)
$713.00
Check Cart for Availability
assay
≥90% (SDS-PAGE)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<1.0 EU/μg protein Endotoxin
shipped in
ambient
storage temp.
−20°C
General description
Recombinant, mouse keratinocyte growth factor (KGF) consisting of amino acids 32-194 and expressed in E. coli. KGF plays an essential role in development, tumorigenesis, angiogenesis, morphogenesis, and wound healing. Mature mouse KGF amino acid sequence is 96% identical with rat, bovine, ovine, equine, and human forms and is active across species.
Biochem/physiol Actions
ED₅₀ = 10-50 ng/ml as measured in a cell proliferation assay using 4MBr-5 monkey epithelial cells.
Physical form
Lyophilized from 0.2 µm sterile-filtered MOPS, Na₂SO₄, EDTA, DTT BSA.
Preparation Note
Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 250 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
Other Notes
Belleudi, F., et al. 2007. Traffic8, 1854.
Finch, P.W. and J.S. Rubin. 2006. J. Natl. Cancer Inst.98, 812.
de Georgi, V., et al. 2007. Dermatol. Clin.25, 477.
Niu, J., et al. 2007. J. Biol. Chem.282, 6001.
Werner, S., et al. 2007. J. Invest. Dermatol.127, 998.
Cardinali, G., et al. 2005. J. Invest. Dermatol.125, 1190.
Geer, D.J., et al. 2005. Am. J. Pathol.167, 1575.
Hsu, YR., et al. 1999. Biochemistry38, 2523.
Qiao, J., et al. 1999. Development126, 547.
Werner, S., 1998. Cytokine Growth Factor Rev.9, 153.
Guo, L., et al. 1996. Genes Dev.10, 165.
Mason, I.J., et al. 1994. Mech. Dev.45, 15.
Finch, P.W. and J.S. Rubin. 2006. J. Natl. Cancer Inst.98, 812.
de Georgi, V., et al. 2007. Dermatol. Clin.25, 477.
Niu, J., et al. 2007. J. Biol. Chem.282, 6001.
Werner, S., et al. 2007. J. Invest. Dermatol.127, 998.
Cardinali, G., et al. 2005. J. Invest. Dermatol.125, 1190.
Geer, D.J., et al. 2005. Am. J. Pathol.167, 1575.
Hsu, YR., et al. 1999. Biochemistry38, 2523.
Qiao, J., et al. 1999. Development126, 547.
Werner, S., 1998. Cytokine Growth Factor Rev.9, 153.
Guo, L., et al. 1996. Genes Dev.10, 165.
Mason, I.J., et al. 1994. Mech. Dev.45, 15.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
1 of 1
This Item | |||
|---|---|---|---|
| description - | description - | description Epiregulin, Mouse, Recombinant is expressed in E. coli with an N-terminal methionine. Inhibits epithelial tumor growth and stimulates the growth of fibroblasts and other cell types. | description - |
| assay ≥90% (SDS-PAGE) | assay ≥97% (SDS-PAGE) | assay ≥97% (SDS-PAGE) | assay ≥97% (SDS-PAGE) |
| form solid | form solid | form liquid | form solid |
| impurities <1.0 EU/μg protein Endotoxin | impurities <1.0 EU/μg protein Endotoxin | impurities <1.0 EU/μg protein Endotoxin | impurities <1.0 EU/μg protein Endotoxin |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in ambient |
| storage condition OK to freeze | storage condition OK to freeze | storage condition OK to freeze | storage condition OK to freeze |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
signalword
Danger
hcodes
Hazard Classifications
vPvM
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