422709

KN-92

KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca²⁺/CaM Kinase II inhibitor.

• Synonym(s): KN-92, 2-[N-(4-Methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate
• Empirical Formula (Hill Notation): C₂₄H₂₅ClN₂O₃S · xH₃PO₄
• CAS Number: 1135280-28-2
• Molecular Weight: 456.98
• MDL number: MFCD24369012
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• SMILES string: [P](=O)(O)(O)O.[S](=O)(=O)(Nc2c(cccc2)CN(C\C=C\c3ccc(cc3)Cl)C)c1ccc(cc1)OC
• InChI: 1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;
• InChI key: XRQHWVVDNMJDEQ-IPZCTEOASA-N
• assay: ≥95% (HPLC)
• form: viscous liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic), protect from light
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• Quality Level: 100

Description

General description

Useful as a negative control for KN-93 (Cat. No. 422708), a Ca²⁺/CaM kinase II inhibitor. Also available as a 5 mM solution in DMSO (Cat. No. 508314).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM kinase II inhibitor

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 4 months at -20°C.

Other Notes

Fan, G.H., et al. 1999. Mol. Pharmacol.56, 39.
Fan, G.H., et al. 1997. Neuropharmacology 36, 1763.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable