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444219-M

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MMP-1 Substrate III, Fluorogenic

An excellent quenched fluorescence substrate for MMP-1.

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Synonym(s):
MMP-1 Substrate III, Fluorogenic
Empirical Formula (Hill Notation):
C51H72N14O12S
Molecular Weight:
1105.27

Quality Level

Assay

≥94% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

yellow

solubility

50% acetic acid: soluble

fluorescence

λex ~365 nm
λem ~450 nm

storage temp.

−20°C

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This Item
444221444256539141
form

solid

form

solid

form

lyophilized solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

color

yellow

color

yellow

color

red

color

white

solubility

50% acetic acid: soluble

solubility

50% acetic acid: 10 mg/mL

solubility

DMSO: soluble, Tris-buffered saline, pH 7.6: soluble

solubility

DMSO: 50 mg/mL

General description

An excellent quenched fluorescence substrate for MMP-1. Has a better kcat/Km value than the MMP Substrate (Cat. No. 444207).
Quenched fluorescence substrate for MMP-1 (excitation maximum: 365 nm; emission maximum: 450 nm). Has a better kcat/Km value than the MMP-Substrate (Cat. No. 444207).

Biochem/physiol Actions

Primary Target
Quenched fluorescence substrate for MMP-1

Warning

Toxicity: Standard Handling (A)

Sequence

DNP-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abu = L-α-aminobutyryl; Abz = 2-aminobenzoyl]

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

McGeehan, G.M., et al. 1994. J. Biol. Chem.269, 32814.
Green, M., et al. 1992. Medicinal Chemistry Annual Meeting, poster (Abstr. 41).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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