444224

Sigma-Aldrich

MMP-2/MMP-9 Substrate II - Calbiochem

An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B).

Synonym(s):
MMP-2/MMP-9 Substrate II - Calbiochem, Ac-Pro-Leu-Gly-(2-mercapto-4-methylpentanoyl)-Leu-Gly-OEt, Gelatinase A/Gelatinase B Substrate II
Empirical Formula (Hill Notation):
C31H53N5O8S
Molecular Weight:
655.85
Pricing and availability is not currently available.

storage conditions

-20C

Quality Level

assay

≥97% (HPLC)

form

solid

mfr. no.

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

water: 1 mg/mL
50% acetic acid: 10 mg/mL

shipped in

ambient

General description

An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay for Type IV collagenases MMP-2 (gelatinase A) and MMP-9 (gelatinase B). Acts as a substrate for vertebrate collagenase. Cleavage is monitored at 324 nm.
An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Also acts as a substrate for vertebrate collagenase. Cleavage is monitored at 324 nm.

Packaging

5 mg in Plastic ampoule

Biochem/physiol Actions

Primary Target
Substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B).
Product does not compete with ATP.
Reversible: no
Cell permeable: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Pro-Leu-Gly-SCH[CH₂CH(CH₃)₂]-CO-Leu-Gly-OC₂H₅

Reconstitution

Unstable in solution; reconstitute just prior to use.

Other Notes

Weingarten, H., et al. 1985. Anal. Biochem. 147, 437.
Weingarten, H., et al. 1985. Biochemistry 24, 6730.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin

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