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481920-M

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NAAG

NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system.

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Synonym(s):
NAAG, N-Acetyl-Asp-Glu, N-acetylaspartylglutamate;Spaglumic acid
Empirical Formula (Hill Notation):
C11H16N2O8
CAS Number:
Molecular Weight:
304.25
MDL number:

Quality Level

Assay

≥98% (TLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 50 mg/mL
methanol: 50 mg/mL

storage temp.

2-8°C

InChI

1S/C11H16N2O8.Mg/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16;/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21);/q;+2/p-2/t6-,7-;/m0./s1

InChI key

BQAXDBLSAIPBND-LEUCUCNGSA-L

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G2128G162604-855
NAAG NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system.

Millipore

481920-M

NAAG

form

powder

form

-

form

powder

form

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

Upstate®

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

storage condition

-

color

white

color

-

color

white to off-white

color

-

solubility

DMSO: 50 mg/mL, methanol: 50 mg/mL

solubility

-

solubility

-

solubility

-

General description

NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system. It remains uncertain whether this compound activates NMDA receptors; however, it is clearly demonstrated to act as a selective agonist of mGluR3, both in vitro and in vivo.

Warning

Toxicity: Regulatory Review (Z)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Neale, J., et al. 2011. J. Neurochem.12, in press; Neal, J., et al. 2011. J. Neurochem.118, 490; Adedoyin, M., et al. 2010. Mol. Pain6, 60; Chopra M., et al. 2009. J. Pharmacol. Exp. Ther.330, 212; Fricker, A., et al. 2009. Neuropharmacology56, 1060; Neale, J.,et al. 2005. Trends Pharmacol. Sci.29, 477; Westbrook, G., et al. 1986. J. Neurosci.11, 3385; Koller, K., et al. 1984. J. Neurochem.43, 1136; Curatolo, A., et al. 1965, J. Neurochem.12, 339.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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