494460

Octyl β-D-glucopyranoside

ULTROL^® Grade, ≥99% (TLC), non-ionic detergent to solubilize membrane-bound proteins in their native state

• Synonym(s): n-Octyl-β-D-glucopyranoside, ULTROL^® Grade, OG, n-Octylglucoside
• Empirical Formula (Hill Notation): C₁₄H₂₈O₆
• CAS Number: 29836-26-8
• Molecular Weight: 292.37
• MDL number: MFCD00063288
• UNSPSC Code: 12161902
• NACRES: NA.21

Properties

• Quality Level: 100
• assay: ≥99% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• aggregation number: 84
• impurities: ≤0.05% n-octanol
• color: white
• CMC: 20 - 25 mM
• solubility: water: 100 mg/mL
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OCCCCCCCC
• InChI: 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
• InChI key: HEGSGKPQLMEBJL-RKQHYHRCSA-N

Description

General description

A highly purified nonionic detergent intended for solubilizing membrane-bound proteins in their native state, and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-15 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Absorbance (10%, H₂O, 260 nm):≤0.3; conductivity (100 mM, H₂O):≤100 µmhos.

Highly purified non-ionic detergent intended for solubilizing membrane-bound proteins in their native state. Aggregation number: 84.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, store in the refrigerator (4°C) under sterile conditions. Aqueous stock solutions are stable for 3 months at 4°C. Solutions are susceptible to hydrolysis (especially in strong acid) and enzymatic degradation.

Other Notes

Hoshino, T., et al. 1992. J. Biol. Chem.267, 21313.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable