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MilliporeSigma

5.05016

Sigma-Aldrich

CX546

Synonym(s):

CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546

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10 MG
$180.00

About This Item

Empirical Formula (Hill Notation):
C14H17NO3
CAS Number:
Molecular Weight:
247.29
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

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$180.00


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assay

≥98% (TLC)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

DMSO: soluble

storage temp.

2-8°C

SMILES string

N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2

InChI

1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2

InChI key

LJUNPHMOGNFFOS-UHFFFAOYSA-N

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This Item
HPA0148215.04913155306-M
CX546

5.05016

CX546

assay

≥98% (TLC)

assay

-

assay

≥99% (HPLC)

assay

≥98% (HPLC)

form

solid

form

buffered aqueous glycerol solution

form

solid

form

powder, solution

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: soluble

solubility

-

solubility

DMSO: 100 mM

solubility

DMSO: 100 mg/mL

General description

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

Biochem/physiol Actions

Primary Target
AMPA

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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