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5.05419

Sigma-Aldrich

α,β-Methyleneadenosine 5′-triphosphate lithium salt

≥93% (HPLC), powder, P2X purinergic receptor agonist, Calbiochem®

Synonym(s):

α,β-methylene ATP, αβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt

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5 MG
$266.00

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5 MG
$266.00

About This Item

CAS Number:
104809-20-3
MDL number:
MFCD00148925
UNSPSC Code:
41106305
NACRES:
NA.77

$266.00

Check Cart for Availability
Request a Bulk Order

Product Name

α,β-methylene ATP,

assay

≥93% (HPLC)

Quality Level

100

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

white

solubility

water: 100 mg/mL

storage temp.

−20°C

SMILES string

[Li+].[P](=O)([O-])(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2c3ncnc(c3nc2)N)C[P](=O)(O[P](=O)(O)O)O

InChI

1S/C11H18N5O12P3.Li/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25;/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25);/q;+1/p-1/t5-,7-,8-,11-;/m1./s1

InChI key

NVHVREPTGDOYIC-YCSZXMBFSA-M

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α,β-methylene ATP

5.05419

α,β-methylene ATP

Oxidized ATP (oATP)

5.05758

Oxidized ATP (oATP)

Anti-P2X4 receptor Antibody, clone 12-10H

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Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate ≥93% (HPLC), powder

A2647

Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate

form

powder

form

powder

form

-

form

powder

assay

≥93% (HPLC)

assay

≥97% (HPLC)

assay

-

assay

≥93% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

solubility

water: 100 mg/mL

solubility

water: 50 mg/mL

solubility

-

solubility

H2O: 50 mg/mL

General description

A metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.

Biochem/physiol Actions

Primary Target
P2X
Reversible: yes

Warning

Toxicity: Standard Handling (A)

Other Notes

Sawyer, G.W., et al. 2000. Br. J. Pharmacol.129, 1458.
Komori, S., et al. 1988. Br. J. Pharmacol.94, 9.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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