5.05875
(+)-Bicuculline
Synonym(s):
(+)-Bicuculline, GABA A Receptor Antagonist, Bicuculline
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About This Item
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assay
≥98% (HPLC)
Quality Level
form
solid
potency
740 nM IC50
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
pale yellow
solubility
DMSO: soluble
Storage temp.
−20°C
SMILES string
N1([C@@H](c5c(cc6c(c5)OCO6)CC1)[C@@H]2OC(=O)c3c4c(ccc32)OCO4)C
InChI
1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
InChI key
IYGYMKDQCDOMRE-ZWKOTPCHSA-N
1 of 4
This Item | 14340 | PHL80371 | 5.05986 |
---|---|---|---|
assay ≥99% (HPLC) | assay ≥97.0% (TLC) | assay ≥98.0% (HPLC) | assay ≥98% (HPLC) |
form solid | form powder | form - | form solid |
manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename PhytoLab | manufacturer/tradename Calbiochem® |
Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
storage temp. −20°C | storage temp. - | storage temp. 2-8°C | storage temp. 2-8°C |
solubility DMSO: soluble | solubility - | solubility - | solubility water: 25 mM |
General description
Warning
Other Notes
Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
Minocha, A., and Galligan, J.J. 1993. Eur. J. Pharmacol.230, 187.
Robert K.A., et al. 1993. Cardiovasc. Pharmacol.21, 156.
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1
Storage Class
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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