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5.05894

Sigma-Aldrich

CGP 7930

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Synonym(s):
CGP 7930, GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930
Empirical Formula (Hill Notation):
C19H32O2
CAS Number:
Molecular Weight:
292.46

assay

≥98% (HPLC)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

pale yellow

solubility

DMSO: 100 mM
ethanol: 100 mM

storage temp.

2-8°C

InChI

1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3

InChI key

XLWJPQQFJNGUPA-UHFFFAOYSA-N

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5.097085.04842AB2255
vibrant-m

5.05894

CGP 7930

vibrant-m

5.09708

SKF-97541

vibrant-m

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CGP 37849

vibrant-m

AB2255

Anti-GABA B Receptor R2 Antibody

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥99% (HPLC)

assay

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

DMSO: 100 mM, ethanol: 100 mM

solubility

water: 100 mM

solubility

H2O: 100 mM

solubility

-

General description

A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents.

Warning

Toxicity: Standard Handling (A)

Other Notes

Adams, C. et al., 2007. CNS Drug Rev.13, 308.
Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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