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5.08017

Sigma-Aldrich

nor-Binaltorphimine Dihydrochloride

≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem

Synonym(s):

nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine

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About This Item

Empirical Formula (Hill Notation):
C40H43N3O6 · 2HCl
CAS Number:
Molecular Weight:
734.71
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

product name

nor-Binaltorphimine Dihydrochloride,

assay

≥98% (HPLC)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white to off-white

solubility

water: 50 mM

storage temp.

−20°C

InChI

1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2

InChI key

GYEXSFKLGQBRBJ-UHFFFAOYSA-N

General description

A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.

Biochem/physiol Actions

Primary Target
kappa opioid receptor

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kishioka, S., et al. 2013. Neurosci. Letters.In press.

Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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