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539142

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Proteasome Substrate III, Fluorogenic

Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.

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Synonym(s):
Proteasome Substrate III, Fluorogenic, Suc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
Empirical Formula (Hill Notation):
C40H53N5O10
Molecular Weight:
763.88

Quality Level

assay

≥98% (HPLC)

form

amorphous solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 50 mg/mL

fluorescence

λex ~380 nm
λem ~460 nm

shipped in

ambient

storage temp.

−20°C

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This Item
539141539149264151
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, desiccated, protect from light

General description

Fluorogenic proteasome substrate. Also acts as a substrate for calpain, chymotrypsin, and ingensin.

Specificity

Inhibits serine proteases and cysteine proteases.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Proteasome
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Suc-Leu-Leu-Val-Tyr-AMC

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Anderson, M., et al. 1999. Exp. Eye Res.69, 129.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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