539735
PTP1B, Human, Recombinant, E. coli
Synonym(s):
Protein Tyrosine Phosphatase 1B
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About This Item
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
liquid
specific activity
≥20 U/mg
mol wt
37,400 g/mol
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−70°C
Gene Information
human ... PTP1B(5770)
General description
Recombinant, human PTP1B expressed in E. coli. PTP1B, an ubiquitous nontransmembrane protein tyrosine phosphatase, was originally identified in human placenta. This highly active enzyme is useful for the study of tyrosine phosphatase kinetics, substrate specificity, and for screening inhibitors. PTP1B comprises three domains: an N-terminal catalytic domain (1–300), a regulatory domain (301–400), and a C-terminal domain (401–435) that is accountable for directing the enzyme to the endoplasmic reticulum (ER) membrane.[1]
Application
Biochem/physiol Actions
Packaging
Warning
Unit Definition
Physical form
Reconstitution
Other Notes
Liu, F., et al. 1996. J. Biol. Chem.271, 31290.
Legal Information
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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