573462

Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide

≥98% (HPLC), chromogenic Cathepsin G substrate, solid

• Synonym(s): Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide
• Empirical Formula (Hill Notation): C₃₀H₃₆N₆O₉
• CAS Number: 70967-97-4
• Molecular Weight: 624.64
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00077161
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100
• Storage condition: OK to freeze, desiccated

Properties

• Product Name: Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide, Sensitive chromogenic substrate for human leukocyte cathepsin G that is not reactive with elastase.
• SMILES string: [N+](=O)([O-])c1ccc(cc1)N[C@@H](Cc3ccccc3)C(=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)O)C)C
• InChI: 1S/C30H36N6O9/c1-18(31-25(37)14-15-26(38)39)27(40)32-19(2)30(43)35-16-6-9-24(35)29(42)34-28(41)23(17-20-7-4-3-5-8-20)33-21-10-12-22(13-11-21)36(44)45/h3-5,7-8,10-13,18-19,23-24,33H,6,9,14-17H2,1-2H3,(H,31,37)(H,32,40)(H,38,39)(H,34,41,42)/t18-,19-,23-,24-/m0/s1
• InChI key: NZSFNPKTEBHXQS-WJNSRDFLSA-N
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated
• color: white to off-white
• solubility: DMSO: 100 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• Quality Level: 100

Description

Biochem/physiol Actions

Cell permeable: no

Primary Target
Chromogenic substrate for human leukocyte cathepsin G

Product does not compete with ATP.

Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

Sensitive chromogenic substrate for human leukocyte cathepsin G that is not reactive with elastase. Also, sensitive substrate for chymotrypsin, capable of detecting nanogram amounts.

Other Notes

Barrett, A.J. 1981. Methods Enzymol.80, 561.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable