The purity of this product is not determined. This product is sold by units, with a minimum activity of 1800 units per milligram protein. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate under ‘Certificate of Analysis’:
https://www.sigmaaldrich.com/product/mm/605157#product-documentation
605157
Thrombin, Bovine
Synonym(s):
Thrombin, Bovine
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| Size/SKU | Availability | Price |
|---|---|---|
1 kU | Check Cart for Availability | $104.00 |
About This Item
Specific activity:
≥1800 NIH units/mg protein, ≥50 NIH units/mg dry wt
description
Merck USA index - 14, 9383
Quality Segment
form
lyophilized
specific activity
≥1800 NIH units/mg protein, ≥50 NIH units/mg dry wt
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
0.05 M NaCl: ≤2000 NIH units/mL, water: >2000 NIH units/mL
shipped in
ambient
storage temp.
−20°C
General description
Native, bovine thrombin. Key enzyme in the coagulation cascade. Converts fibrinogen into fibrin and activates factor XIII, which cross-links and stabilizes the fibrin polymer. Has a pH of 6.0-7.5 in a 7% solution.
Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
Lyophilized from 50 mM Sodium Citrate, 0.2 M NaCl, 0.1% PEG-8000, pH 6.5.
Preparation Note
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 2 months at -70°C.
From Catalog:
Desc. Field- added "Key enzyme that activates factor XIII and converts fibronogen into fibrin."
From Catalog:
Desc. Field- added "Key enzyme that activates factor XIII and converts fibronogen into fibrin."
Other Notes
One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
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This Item | |||
|---|---|---|---|
| specific activity ≥1800 NIH units/mg protein, ≥50 NIH units/mg dry wt | specific activity ≥1000 NIH units/mg protein | specific activity ≥1800 NIH units/mg protein | specific activity 600-2,000 NIH units/mg protein (biuret) |
| form lyophilized | form lyophilized | form lyophilized | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in - |
| solubility 0.05 M NaCl: ≤2000 NIH units/mL, water: >2000 NIH units/mL | solubility water: 1 mg/mL | solubility water: soluble | solubility - |
| storage condition OK to freeze | storage condition OK to freeze, desiccated | storage condition OK to freeze | storage condition - |
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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What is the purity of this protein?
1 answer-
Helpful?
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If I reconstitute the thrombin with 10 ml of water, hoe many units of thrombin will be present per ml?
1 answer-
Dissolving 1,000 units of thrombin in 10 ml of water results in a concentration of 100 units per ml.
Helpful?
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What volume of water do I reconstitute this powder with for the 1 kU bottle?
1 answer-
1KU can be reconstituted with 200 ul of deionized water just prior to application.
Helpful?
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