666122-M

Urea

Molecular Biology Grade, End product of the urea cycle. A topical keratolytic agent.

• Synonym(s): Urea, Carbamide, Carbonyl Diamide, Carbamide, Carbonyldiamide
• Linear Formula: NH₂CONH₂
• CAS Number: 57-13-6
• Molecular Weight: 60.06
• NACRES: NA.25
• UNSPSC Code: 12352111
• Beilstein/REAXYS Number: 635724
• MDL number: MFCD00008022
• eCl@ss: 32150917
• Assay: ≥98%
• Grade: Molecular Biology

Properties

• grade: Molecular Biology
• Quality Segment: 100
• description: Merck USA index - 14, 9867
• assay: ≥98%
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• mp: 132-135 °C (lit.)
• solubility: water: soluble
• density: 1.335 g/mL at 25 °C (lit.)
• absorption: ≤0.01 at 260 nm, ≤0.01 at 280 nm
• foreign activity: DNases, proteases, RNases, none detected
• storage temp.: 10-30°C
• SMILES string: NC(N)=O
• InChI: 1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
• InChI key: XSQUKJJJFZCRTK-UHFFFAOYSA-N

Description

General description

End product of the urea cycle (absorbance: ≤0.01 at 260 nm and 280 nm). A topical keratolytic agent.

End product of the urea cycle. A topical keratolytic agent.

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable