8.03235

N,N-Dimethylacetamide

for synthesis

• Synonym(s): N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMA
• Linear Formula: CH₃CON(CH₃)₂
• CAS Number: 127-19-5
• Molecular Weight: 87.12
• MDL number: MFCD00008686
• EC Index Number: 204-826-4

Properties

• vapor pressure: 1.76 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥99% (GC)
• form: liquid
• autoignition temp.: 400 °C
• potency: 5830 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 1.7-11.5 % (v/v)
• pH: 4 (20 °C, 200 g/L in H₂O)
• bp: 165-166 °C/1013 hPa
• mp: -20 °C
• transition temp: flash point 64 °C
• solubility: soluble >1000 g/L
• density: 0.94 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
• InChI key: FXHOOIRPVKKKFG-UHFFFAOYSA-N

Description

General description

N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene, vinyl resin, linear polyester, acrylic fiber, plastic, pesticide, and synthetic leather. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.

Application

N,N-Dimethylacetamide is used as a solvent:

• In the synthesis of poly(amide-hydrazide)s–graphene composites.
• In the synthesis of N,N′-1,2-ethanediylbis-(4-hydroxy-pentanamide) and 4-hydroxy-N-(2- hydroxyethyl)-pentanamide based polyurethanes in presence of triethylamine catalyst.

Features and Benefits

N,N-Dimethylacetamide has :

• High dissolution power of various substrate. 
• High capacity to solvate anions.

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.940 - 0.942
Water (K. F.): ≤ 0.30 %
Identity (IR): passes test

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H312 + H332 - H319 - H360D
• Precautionary Statements: P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 147.2 °F - closed cup
• Flash Point(C): 64 °C - closed cup