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8.04518
N-Hydroxysuccinimide
≥99.0% (acidimetric), for peptide synthesis
Synonym(s):
N-Hydroxysuccinimide, 1-Hydroxy-2,5-pyrrolidinedione
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$50.70
$156.00
$505.00
About This Item
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Product Name
N-Hydroxysuccinimide, for synthesis
Quality Level
assay
≥99.0% (acidimetric)
form
crystals
reaction suitability
reaction type: Addition Reactions
pH
5-7 (20 °C, 50 g/L in H2O)
mp
93-100 °C
application(s)
peptide synthesis
SMILES string
N1(C(=O)CCC1=O)O
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
InChI key
NQTADLQHYWFPDB-UHFFFAOYSA-N
1 of 4
This Item | 130672 | 56480 | 774324 |
|---|---|---|---|
| form crystals | form solid | form solid | form solid |
| assay ≥99.0% (acidimetric) | assay 98% | assay ≥97.0% (T) | assay 96% |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| mp 93-100 °C | mp 95-98 °C (lit.) | mp 95-98 °C (lit.) | mp 136-138 °C |
| reaction suitability reaction type: Addition Reactions | reaction suitability - | reaction suitability reaction type: Addition Reactions | reaction suitability - |
| pH 5-7 (20 °C, 50 g/L in H2O) | pH - | pH - | pH - |
Application
- Direct Cα-heteroarylation of structurally diverse ethers: This study showcases a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction, expanding the utility of NHS in organic synthesis. (Liu et al., 2017).
Analysis Note
Melting range (lower value): ≥ 95 °C
Melting range (upper value): ≤ 100 °C
Identity (IR): passes test
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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