8.07572

Pyrazole

for synthesis

• Synonym(s): Pyrazole, 1,2-Diazol
• Empirical Formula (Hill Notation): C₃H₄N₂
• CAS Number: 288-13-1
• Molecular Weight: 68.08
• MDL number: MFCD00005234
• UNSPSC Code: 12352005
• EC Index Number: 206-017-1
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥99.0% (GC)
• form: crystals
• potency: 1010 mg/kg LD₅₀, oral (Rat)
• mp: 66-68 °C
• storage temp.: 2-30°C
• SMILES string: [nH]1nccc1
• InChI: 1S/C3H4N2/c1-2-4-5-3-1/h1-3H,(H,4,5)
• InChI key: WTKZEGDFNFYCGP-UHFFFAOYSA-N

Description

Application

• Uranium extraction with pyrazole-based polymers: A study demonstrated the capability of a pyrazole-based porous organic polymer to extract uranium, offering potential applications in environmental cleanup and nuclear waste management (Yu et al., 2024).


• Pyrazole derivatives for agricultural fungicides: Novel pyrazole-4-carboxamide derivatives containing an oxime ether group were synthesized and evaluated as potential succinate dehydrogenase inhibitors (SDHIs) for controlling Rhizoctonia solani in crops, suggesting their utility in agriculture (Luo et al., 2024).


• Pyrazole-based fluorescent probes: Research on the synthesis and application of specific N(2)H(4) fluorescent probes based on the pyrazole structure demonstrated their utility with aggregation-induced emission (AIE) properties, highlighting potential applications in bioimaging (Yang et al., 2024).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 66 °C
Melting range (upper value): ≤ 69 °C
Identity (IR): passes test

Safety Information

• pictograms: GHS05,GHS06,GHS08
• signalword: Danger
• hcodes: H302 - H311 - H315 - H318 - H373 - H412
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable