MilliporeSigma

8.17001

SAFC

Polyethylene glycol 200

EMPROVE® ESSENTIAL, DAB 8

Synonym(s):
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 200, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
EC Index Number:
500-038-2

Agency

DAB 8

Quality Level

vapor pressure

<0.01 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

form

liquid

autoignition temp.

350 °C (DIN 51794)

pH

5-7 (20 °C, 100 g/L in H2O)

bp

>150 °C

mp

-50 °C

transition temp

flash point 180 °C

solubility

soluble 70 g/L

density

1.124 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solubility enhancement

storage temp.

no temp limit

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Inchi Key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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This Item
8.170028.170038.17019
Polyethylene glycol 200 EMPROVE&#174; ESSENTIAL, DAB 8

SAFC

8.17001

Polyethylene glycol 200

Polyethylene glycol 300 EMPROVE&#174; ESSENTIAL, Ph. Eur.

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8.17002

Polyethylene glycol 300

Polyethylene glycol 400 EMPROVE&#174; ESSENTIAL, Ph. Eur., JP

SAFC

8.17003

Polyethylene glycol 400

Polyethylene glycol 3000 EMPROVE&#174; ESSENTIAL, Ph. Eur.

SAFC

8.17019

Polyethylene glycol 3000

mp

-50 °C

mp

-15--10 °C

mp

5 °C

mp

55-58 °C

transition temp

flash point 180 °C

transition temp

flash point 220 °C

transition temp

flash point >200 °C

transition temp

flash point 270 °C

density

1.124 g/cm3 at 20 °C

density

1.13 g/cm3 at 20 °C

density

1.13 g/cm3 at 20 °C

density

1.21 g/cm3 at 20 °C

storage temp.

no temp limit

storage temp.

no temp limit

storage temp.

15-25°C

storage temp.

no temp limit

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

500

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

281.5 °F - closed cup

Flash Point(C)

138.6 °C - closed cup


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