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Key Documents

8.19015

Sigma-Aldrich

Polyethylene glycol

3000, for synthesis

Synonym(s):

Poly(ethylene glycol), Polyethylene glycol 3000, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 3000, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
13111021
EC Index Number:
500-038-2
NACRES:
NA.22

vapor pressure

<0.1 hPa ( 20 °C)

Quality Level

form

liquid

autoignition temp.

420 °C

potency

28000 mg/kg LD50, oral (Rat)
>20000 mg/kg LD50, skin (Rabbit)

pH

4-7 (20 °C, 100 g/L in H2O)

mp

55-58 °C

transition temp

flash point 270 °C

density

1.21 g/cm3 at 20 °C

bulk density

400‑500 kg/m3

storage temp.

2-30°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application

Polyethylene glycol 3000 can be used as:
  • A surface-modification agent in the synthesis of monodispersed magnetite colloidal magnetic nanoparticles.
  • A precipitating agent in the crystallization of oligoxyloglucan reducing-end specific cellobiohydrolase (OXG-RCBH) by the hanging-drop vapor diffusion method.
  • A solvent and phase-transfer catalyst (PTC) in the application of aqueous biphasic reactive extraction.
  • An additive in the preparation of polysulfone membrane to study the porometry.

Analysis Note

Hydroxyl value: 34 - 42
Melting range (lower value): ≥ 55 °C
Melting range (upper value): ≤ 59 °C
Average molecular mass: 2700 - 3300
Identity (IR): passes test

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup


Certificates of Analysis (COA)

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Polyethylene glycol and solutions of polyethylene glycol as green reaction media
Chen Ji, et al.
Green Chemistry, 7(2) (2005)
Porometry studies of the polysulfone membranes on addition of poly (ethylene glycol) in gelation bath during preparation
Yogesh SJ, et al.
Journal of the Mexican Chemical Society, 52(2) (2008)
Katsuro Yaoi et al.
Acta crystallographica. Section D, Biological crystallography, 59(Pt 10), 1838-1839 (2003-09-23)
A novel xyloglucan-specific exo-beta-glycosidase, oligoxyloglucan reducing-end specific cellobiohydrolase (OXG-RCBH), recognizes the reducing end of oligoxyloglucan and releases two glucosyl residue segments from the main chain. OXG-RCBH was crystallized by the hanging-drop vapour-diffusion method with polyethylene glycol 3000 and polyethylene glycol
Eleftherios Halevas et al.
Journal of inorganic biochemistry, 213, 111271-111271 (2020-10-19)
Targeted tissue drug delivery is a challenge in contemporary nanotechnologically driven therapeutic approaches, with the interplay interactions between nanohost and encapsulated drug shaping the ultimate properties of transport, release and efficacy of the drug at its destination. Prompted by the

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