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8.51005

Sigma-Aldrich

DSC

N,N′-Disuccinimidyl carbonate Novabiochem®

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Synonym(s):
DSC, N,N′-Disuccinimidyl carbonate, Di-(N-Succinimidyl)carbonate
Empirical Formula (Hill Notation):
C9H8N2O7
CAS Number:
Molecular Weight:
256.17
MDL number:
EC Index Number:
277-730-3

Quality Level

product line

Novabiochem®

Assay

≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

188-191 °C

application(s)

peptide synthesis

storage temp.

2-8°C

InChI

1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2

InChI key

PFYXSUNOLOJMDX-UHFFFAOYSA-N

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437202258278.14971
DSC N,N′-Disuccinimidyl carbonate Novabiochem®

Sigma-Aldrich

8.51005

DSC

assay

≥99.0% (HPLC)

assay

≥95.0% (NMR)

assay

≥95%

assay

≥98.0% (HPLC)

form

powder

form

powder

form

powder or crystals

form

solid

mp

188-191 °C

mp

190 °C (dec.) (lit.)

mp

190 °C (dec.) (lit.)

mp

188-191 °C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-30°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

A convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids [1,2,3,4].

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

[1] H. Ogura, et al. (1979) Tetrahedron Lett., 20, 4745.
[2] H. Ogura, et al. (1981) Tetrahedron Lett., 22, 4817.
[3] K. Takeda, et al. (1982) Synth. Commun., 12, 213.
[4] K. Takeda, et al. (1983) TetrahedronLett., 24, 4569.

Linkage

Replaces: 01-62-0006

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 0.50 %
Identity (IR): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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