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8.51014

Sigma-Aldrich

Fmoc-OSu

Novabiochem®

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Synonym(s):
Fmoc-OSu, FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
Empirical Formula (Hill Notation):
C19H15NO5
CAS Number:
Molecular Weight:
337.33
MDL number:
EC Index Number:
433-520-5

Quality Level

product line

Novabiochem®

assay

≥99.0% (HPLC)

form

powder

manufacturer/tradename

Novabiochem®

mp

145-148 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

InChI

1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

InChI key

WMSUFWLPZLCIHP-UHFFFAOYSA-N

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Fmoc-OSu Novabiochem®

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Fmoc N-hydroxysuccinimide ester ≥98.0% (HPLC)

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Fmoc chloride BioReagent, ≥99.0% (HPLC)

23184

Fmoc chloride

Boc-OSu ≥98.0% (CHN)

20430

Boc-OSu

assay

≥99.0% (HPLC)

assay

≥98.0% (HPLC)

assay

≥99.0% (HPLC)

assay

≥98.0% (CHN)

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

-

product line

Novabiochem®

product line

-

product line

BioReagent

product line

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

mp

145-148 °C

mp

150-153 °C (lit.)

mp

61-64 °C, 62-64 °C (lit.)

mp

~95 °C (dec.)

General description

Reagent for the preparation of pure Fmoc-amino acids that are free from contamination by Fmoc-dipeptides [1,2,3].

Literature references

[1] A. Paquet (1982) Can. J. Chem., 60, 976.
[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.

Linkage

Replaces: 01-63-0001

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Numerous glutamine analogues have been reported as irreversible inhibitors of the glucosamine-6-phosphate (GlcN-6-P) synthase in pathogenic Candida albicans in the last 3.5 decades. Among the reported inhibitors, the most effective N3-(4-methoxyfumaroyl)-l-2,3-diaminopropanoic acid (FMDP) has been extensively studied in order to

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