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8.51027

Sigma-Aldrich

Biotin-ONp

Novabiochem®

Synonym(s):
Biotin-ONp, Biotin p-nitrophenyl ester,5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid p-nitrophenyl ester
Empirical Formula (Hill Notation):
C16H19N3O5S
CAS Number:
Molecular Weight:
365.40
MDL number:

Quality Level

product line

Novabiochem®

Assay

≥97.0% (HPLC)
≥98% (TLC)

form

powder

reaction suitability

reaction type: Biotinylations

manufacturer/tradename

Novabiochem®

mp

163-165 °C

application(s)

peptide synthesis

storage temp.

15-25°C

InChI

1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1

InChI key

YUDNXDTXQPYKCA-YDHLFZDLSA-N

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This Item
RES1052B-B7PHR1233B4501
Biotin-ONp Novabiochem®

Sigma-Aldrich

8.51027

Biotin-ONp

BIOTIN

SAFC

RES1052B-B7

BIOTIN

Biotin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1233

Biotin

Biotin ≥99% (HPLC), lyophilized powder

Sigma-Aldrich

B4501

Biotin

assay

≥97.0% (HPLC), ≥98% (TLC)

assay

97.5-100.5%

assay

-

assay

≥99% (HPLC)

form

powder

form

powder

form

-

form

lyophilized powder

reaction suitability

reaction type: Biotinylations

reaction suitability

-

reaction suitability

-

reaction suitability

-

mp

163-165 °C

mp

231-233 °C (lit.)

mp

231-233 °C (lit.)

mp

231-233 °C (lit.)

storage temp.

15-25°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-8°C

Quality Level

200

Quality Level

400

Quality Level

300

Quality Level

300

General description

Pre-activated reagent for the introduction of biotin by solid phase synthesis. More soluble and more reactive than 851023 [1]. This reagents has recently been found to be effective in SPOT synthesis of biotinylated peptides [2].

The product number for this product was previously 01-63-0116.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-63-0116

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): +34.5 - +39.5 °
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Quality

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