8.51027

Biotin-ONp

Novabiochem^®

• Synonym(s): Biotin-ONp, Biotin p-nitrophenyl ester,5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid p-nitrophenyl ester
• Empirical Formula (Hill Notation): C₁₆H₁₉N₃O₅S
• CAS Number: 33755-53-2
• Molecular Weight: 365.40
• MDL number: MFCD15141972

Properties

• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥97.0% (HPLC); ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Biotinylations
• manufacturer/tradename: Novabiochem^®
• mp: 163-165 °C
• application(s): peptide synthesis
• storage temp.: 15-25°C
• InChI: 1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
• InChI key: YUDNXDTXQPYKCA-YDHLFZDLSA-N

Description

General description

Pre-activated reagent for the introduction of biotin by solid phase synthesis. More soluble and more reactive than 851023 [1]. This reagents has recently been found to be effective in SPOT synthesis of biotinylated peptides [2].

The product number for this product was previously 01-63-0116.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-63-0116

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): +34.5 - +39.5 °
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable