MilliporeSigma
All Photos(1)

Documents

8.52000

Sigma-Aldrich

Fmoc-Thr(tBu)-OH

Novabiochem®

Sign Into View Organizational & Contract Pricing

Select a Size

Change View

Select a Size

Change View
Synonym(s):
Fmoc-Thr(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-threonine
Empirical Formula (Hill Notation):
C23H27NO5
CAS Number:
Molecular Weight:
397.46
MDL number:
EC Index Number:
276-261-1

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)
≥98.0% (acidimetric)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

125-135 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

InChI

1S/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/p-1/t14-,20+/m1/s1

InChI key

LZOLWEQBVPVDPR-VLIAUNLRSA-M

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
8.521578.522348.53055
Fmoc-Thr(tBu)-OH Novabiochem®

Sigma-Aldrich

8.52000

Fmoc-Thr(tBu)-OH

Fmoc-D-Thr(tBu)-OH Novabiochem®

Sigma-Aldrich

8.52157

Fmoc-D-Thr(tBu)-OH

Fmoc-D-Thr-OH Novabiochem®

Sigma-Aldrich

8.52234

Fmoc-D-Thr-OH

Boc-Thr(tBu)-OH Novabiochem®

Sigma-Aldrich

8.53055

Boc-Thr(tBu)-OH

assay

≥98% (TLC), ≥98.0% (acidimetric), ≥99.0% (HPLC)

assay

≥97.0% (acidimetric), ≥98% (TLC), ≥99.0% (HPLC)

assay

≥93.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

assay

≥98% (TLC)

form

powder

form

powder

form

powder

form

powder

mp

125-135 °C

mp

-

mp

-

mp

95-98 °C

functional group

hydroxyl

functional group

hydroxyl

functional group

hydroxyl

functional group

hydroxyl

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of threonine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1000

Analysis Note

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.7 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Thr(tBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Thr(tBu)-Thr(tBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Thr-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 7

1 of 7

Fmoc-D-Trp(Boc)-OH Novabiochem®

Sigma-Aldrich

8.52164

Fmoc-D-Trp(Boc)-OH

FMOC-Asn(Trt)-OH N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem®

Sigma-Aldrich

8.52044

FMOC-Asn(Trt)-OH

Fmoc-Asp(OtBu)-OH Novabiochem®

Sigma-Aldrich

8.52005

Fmoc-Asp(OtBu)-OH

Fmoc-Ala-OH Novabiochem®

Sigma-Aldrich

8.52003

Fmoc-Ala-OH

Fmoc-Ser(tBu)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47619

Fmoc-Ser(tBu)-OH

Fmoc-Arg(Pbf)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47349

Fmoc-Arg(Pbf)-OH

Fmoc-Lys(Boc)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47624

Fmoc-Lys(Boc)-OH

Yun Song et al.
Cell reports, 30(8), 2699-2711 (2020-02-27)
The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the

Related Content

Purer Fmocs Means Purer Peptides

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service