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8.52020

Sigma-Aldrich

Fmoc-Tyr(tBu)-OH

Novabiochem®

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Synonym(s):
Fmoc-Tyr(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-tyrosine
Empirical Formula (Hill Notation):
C28H29NO5
CAS Number:
Molecular Weight:
459.53
MDL number:
EC Index Number:
276-262-7

Quality Level

product line

Novabiochem®

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

143-155 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

InChI

1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)

InChI key

JAUKCFULLJFBFN-UHFFFAOYSA-N

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This Item
476238.5200047622
vibrant-m

8.52020

Fmoc-Tyr(tBu)-OH

vibrant-m

47623

Fmoc-Tyr(tBu)-OH

vibrant-m

8.52000

Fmoc-Thr(tBu)-OH

vibrant-m

47622

Fmoc-Thr(tBu)-OH

product line

Novabiochem®

product line

-

product line

Novabiochem®

product line

-

functional group

hydroxyl

functional group

Fmoc

functional group

hydroxyl

functional group

Fmoc, amine, carboxylic acid

Quality Level

400

Quality Level

100

Quality Level

400

Quality Level

100

form

solid

form

powder

form

powder

form

-

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-8°C

General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of tyrosine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

Fmoc-Tyr(tBu)-OH Novabiochem®. CAS 71989-38-3, molar mass 459.55 g/mol.

Linkage

Replaces: 04-12-1037

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Color index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Tyr(tBu) -OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Tyr(tBu)-Tyr(tBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Tyr-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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