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8.52225

Sigma-Aldrich

Fmoc-Met-OPfp

Novabiochem®

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Synonym(s):
Fmoc-Met-OPfp, N-α-Fmoc-L-methionine pentafluorophenyl ester
Empirical Formula (Hill Notation):
C26H20F5NO4S
CAS Number:
Molecular Weight:
537.50
MDL number:

Quality Level

product line

Novabiochem®

assay

≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

130-140 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

InChI

1S/C26H20F5NO4S/c1-37-11-10-18(25(33)36-24-22(30)20(28)19(27)21(29)23(24)31)32-26(34)35-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,32,34)/t18-/m0/s1

InChI key

OKDPSRDTLNXPFQ-SFHVURJKSA-N

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Fmoc-Met-OPfp

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Fmoc-Ile-OPfp

form

powder

form

powder

form

powder

form

powder

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

storage temp.

15-25°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

15-25°C

mp

130-140 °C

mp

-

mp

130-140 °C

mp

-

General description

Pre-formed pentafluorophenyl ester for coupling of methionine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1512

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -14.5 - -11.5 °
DCU (DC (0004)): ≤ 2 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


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