8.53018

Boc-Lys(2-Cl-Z)-OH

(cryst) Novabiochem^®

• Synonym(s): Boc-Lys(2-Cl-Z)-OH, N-α-t.-Boc-N-ε-2-chloro-CBZ-L-lysine
• Empirical Formula (Hill Notation): C₁₉H₂₇ClN₂O₆
• CAS Number: 54613-99-9
• Molecular Weight: 414.88
• MDL number: MFCD00356585
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥95.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Boc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 70-73 °C
• application(s): peptide synthesis
• functional group: amine
• storage temp.: 2-8°C
• SMILES string: Clc1c(cccc1)COC(=O)NCCCCC(NC(=O)OC(C)(C)C)C(=O)O
• InChI: 1S/C19H27ClN2O6/c1-19(2,3)28-18(26)22-15(16(23)24)10-6-7-11-21-17(25)27-12-13-8-4-5-9-14(13)20/h4-5,8-9,15H,6-7,10-12H2,1-3H3,(H,21,25)(H,22,26)(H,23,24)
• InChI key: ATUMDPHEFWGCJF-UHFFFAOYSA-N

Description

General description

Standard building block for introduction of lysine amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] K. Noda, et al. (1969) Bull. Chem. Soc. Jpn., 43, 1883.
^[2] B. W. Erickson, et al. (1973) J. Am. Chem. Soc., 95, 3757.

Linkage

Replaces: 04-12-0068

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -12.0 - -10.0 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Solubility (1mmoll in 2ml DCM): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Enantiomeric purity: ≥ 99.5 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable