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8.55047

Sigma-Aldrich

NovaPEG Rink Amide resin

Novabiochem®

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Quality Level

product line

NovaPEG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

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This Item
8.550018.551258.55130
vibrant-m

8.55047

NovaPEG Rink Amide resin

vibrant-m

8.55001

Rink Amide resin (100-200 mesh)

vibrant-m

8.55125

NovaPEG Rink Amide resin LL

product line

NovaPEG, Novabiochem®

product line

Novabiochem®

product line

NovaPEG, Novabiochem®

product line

Novabiochem®

Quality Level

200

Quality Level

400

Quality Level

200

Quality Level

400

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

form

beads

form

beads

form

beads

form

powder

General description

An excellent acid-labile resin for the continuous flow and batch Fmoc SPPS of peptide amides. This resin is prepared by derivatization of NovaPEG amino resin with the modified Rink linker. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. The high hydrophilicity was also found to benefit on-resin immunoassays with one-bead-one-peptide libraries [1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0473

Analysis Note

Colour (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.60 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
PEG based resin; 35 - 100 mesh

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Articles

Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

Protocols

Review methods and resins for attaching amino acids and peptides, including Merrifield, trityl-based, and hydroxymethyl-functionalized resins. Resin-immobilized peptides can be used for various downstream applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service