8.55064

Sigma-Aldrich

NovaSyn® TG hydroxy resin

Novabiochem®

CAS Number:

storage conditions

Store below +30°C.

Quality Level

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

functional group

alcohol

storage temp.

2-30°C

General description

NovaSynTG hydroxy resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol, in which the ends of the PEG chains have been functionalized with hydroxyl groups. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling across a wide range of solvents from toluene to water [1-3], making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis.

This support has been used for the solid phase immobilization of carboxylic acids [4-9], with cleavage by saponification with dilute aq. NaOH.

The product number for this product was previously 01-64-0096.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-64-0096

Analysis Note

Color (visual): white to amber to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
130 µm beads

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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