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8.56043

Sigma-Aldrich

Fmoc-Glu(NovaSyn®TGA)-OAll

Novabiochem®

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Quality Level

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

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Fmoc-Glu(NovaSyn®TGA)-OAll

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Fmoc-His(Trt)-NovaSyn® TGT

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Fmoc-Leu-NovaSyn® TGA

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

General description

Pre-loaded resin for synthesis of peptide acids containing a C-terminal glutamic acid amino-acid residue by Fmoc SPPS.
The base NovaSyn TG is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol. Peptide synthesis occurs at the ends of the PEG chains which have been functionalized with a TFA-labile Wang-type linker. NovaSyn TG resins are ideal for the synthesis of difficult and long peptides as the PEG helps solvate the growing peptide chains and increase site isolation, thereby improving synthesis efficiency and peptide product quality. The 90 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel peptide

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-2681

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.10 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The base resin is amino PEG-PS-copolymer (90 µm), functionalized with 4-hydroxymethylphenoxyacetic acid.

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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