A novel resin for the preparation of peptide substrates based on 3-amino-7-methylcoumarin (AMC) by Fmoc SPPS. Following Fmoc removal with 20% piperidine, peptide assembly can be effected using standard coupling methods. Treatment with 95% TFA releases the peptide-AMC directly from the solid phase.
Colour (visual): white to yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.60 mmol/g Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh. The resin is endcapped after coupling the amino acid derivative.
Other Notes
Replaces: 04-12-3917
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.
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