Nicotinic acetylcholine receptors, also known as nAChRs, belong to a family of proteins called ligand gated ion channels and are widely expressed throughout the nervous system. nAChRs are made up of 5 subunits (two α and three β). Subunits α4 and β2 (α4β2) is the main receptor in the mammalian brain and has been associated with the positive reinforcing effects of nicotine. The relative contribution of nAChRs β2 and β4 are not well understood because the subunit structure that mediates synaptic transmission in the peripheral nervous system is unknown.
This antibody recognizes Nicotinic Acetylcholine Receptor β2.
This antibody is generated from rabbits immunized with a KLH-conjugated linear peptide selected from residues of Nicotinic Acetylcholine Receptor β2.
Detect Nicotinic Acetylcholine Receptor β2 using this Anti-Nicotinic Acetylcholine Receptor β2 Antibody validated for use in WB.
Routinely evaluated by Western Blot in rat e16 brain lysate.
Western Blot Analysis: : 1:20,000 dilution of this lot detected Nicotinic Acetylcholine Receptor β2 on 10 µg of rat e16 brain lysate.
Approx. 55 kDa
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.