AB1936
Anti-Integrin α2 Antibody
serum, Chemicon®
Synonym(s):
CD49b
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 μL | Check Cart for Availability | $490.00 |
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, IP, RIA, WB
Citations:
50
$490.00
Check Cart for Availability
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
chicken, rat, hamster, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, radioimmunoassay: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGA2(3673)
General description
160kDa
Immunogen
Synthetic peptide derived from the COOH terminal sequence (cytoplasmic domain) of the human alpha2 integrin subunit {KYEKMTKNPDEODETTELSS}
Application
Anti-Integrin α2 Antibody detects level of Integrin α2 & has been published & validated for use in ELISA, IF, IH, IP, RIA & WB.
Immunofluorescence: 1:500 (suggested for use on acetone-fixed tissue only)
ELISA/RIA: 1:1000
Western blot: 1:1000 The antibody has been used to report alpha2 expression in HUVECs during tubule-like structure formation in collagen (Deroanne, 1996). Recognizes ~160kDa alpha 2 subunit
Immunoprecipitation: 5 μL precipitates alpha2/beta1 from 5 x 106 cells.
Immunohistochemistry: 1:500
Optimal working dilutions must be determined by end user.
ELISA/RIA: 1:1000
Western blot: 1:1000 The antibody has been used to report alpha2 expression in HUVECs during tubule-like structure formation in collagen (Deroanne, 1996). Recognizes ~160kDa alpha 2 subunit
Immunoprecipitation: 5 μL precipitates alpha2/beta1 from 5 x 106 cells.
Immunohistochemistry: 1:500
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Human alpha2 integrin subunit. Specificity determined by immunoprecipitation from a detergent extract of 35S methionine labeled endothelial cells. The epitope recognized is on the cytoplasmic domain of the protein and is thus intracellular. Shows no cross-reactivity to alpha1, alpha3, alpha4, alpha5, alpha6, or alphaV subunits.
Physical form
Neat rabbit antiSerum. Liquid with 0.05% sodium azide
Unpurified
Preparation Note
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Skin (basement membrane), High grade ovarian tumors
Skin (basement membrane), High grade ovarian tumors
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
This Item | |||
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| antibody form serum | antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source rabbit | biological source mouse | biological source mouse | biological source mouse |
| Gene Information human ... ITGA2(3673) | Gene Information human ... ITGA2(3673) | Gene Information human ... ITGA2(3673) | Gene Information human ... ITGA2(3673) |
| species reactivity chicken, rat, hamster, mouse, human | species reactivity human | species reactivity human, pig | species reactivity human, canine, pig |
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Chiara Pelillo et al.
Journal of cellular biochemistry, 116(10), 2385-2396 (2015-04-11)
Colorectal cancer (CRC) metastasis dissemination to secondary sites represents the critical point for the patient's survival. The microenvironment is crucial to cancer progression, influencing tumour cell behaviour by modulating the expression and activation of molecules such as integrins, the cell-extracellular
Juha K Rantala et al.
Microarrays (Basel, Switzerland), 2(2), 97-114 (2013-01-01)
Over the past decade, great strides have been made in identifying gene aberrations and deregulated pathways that are associated with specific disease states. These association studies guide experimental studies aimed at identifying the aberrant genes and networks that cause the
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex.
Lee, SH; Hatakeyama, S; Yu, SY; Bao, X; Ohyama, C; Khoo, KH; Fukuda, MN; Fukuda, M
The Journal of Biological Chemistry null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1936 | 04053252330384 |