AB5066P

Anti-Norepinephrine Transporter Antibody

Name: Anti-Norepinephrine Transporter Antibody
Brand: MM
Price: 624 USD

Chemicon^®, from rabbit

Synonym(s):

NET

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50 μG

$624.00

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Key Documents

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Product Name

Anti-Norepinephrine Transporter Antibody, Chemicon^®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_001043.2

UniProt accession no.

P23975

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SLC6A2(6530), SLC6A5(9152)

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Show Differences

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This Item	MAB5620	AB1594P	AB5802
Sigma-Aldrich AB5066P Anti-Norepinephrine Transporter Antibody	Sigma-Aldrich MAB5620 Anti-Norepinephrine Transporter Antibody	Sigma-Aldrich AB1594P Anti-Serotonin Transporter Antibody	Sigma-Aldrich AB5802 Anti-Dopamine Transporter Antibody, extracellular Loop 2
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity purified immunoglobulin	antibody form ascites fluid	antibody form affinity purified immunoglobulin	antibody form affinity purified immunoglobulin
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in dry ice
technique(s) ELISA: suitable, western blot: suitable	technique(s) immunohistochemistry: suitable	technique(s) ELISA: suitable, western blot: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable
UniProt accession no. P23975	UniProt accession no. P23975	UniProt accession no. P31645	UniProt accession no. Q01959

Application

This Anti-Norepinephrine Transporter Antibody is validated for use in ELISA, WB for the detection of Norepinephrine Transporter.

Western blot: 1-10 μg/mL (Chemiluminescence technique): NET can exist is at least two forms, a highly glycosylated ~80kDa form is the most common in brain, and a lessly glycosylated 54kDa form is also seen in some regions and tissues.

ELISA: 1:10,000-1:100,000 (50-100 ng immunogen peptide/well) Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Specific for Norepinephrine Transporter (NET). Norepinephrine Transporter is a 617 amino acid long integral membrane protein belonging to the Sodium:Neurotransmitter Symporter family (Bruss et al. 1995; Melikian et al. 1994; Pacholczyk et al. 1991) The immunogen peptide shows no significant homology with other other known proteins.

General description

80 & 54 kDa

Immunogen

A 22 amino acid peptide sequence mapping to the 1st extracellular domain of rat NET.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA .

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein.

Christophe Wersinger et al.

The European journal of neuroscience, 24(11), 3141-3152 (2006-12-13)

Alpha-synuclein (alpha-Syn) has been studied in the context of Parkinson's disease, but its normative role remains elusive. We have shown that alpha-Syn regulates the homeostasis of dopaminergic and serotonergic synapses, through trafficking of the dopamine and serotonin transporter, respectively. In

Regulation of transepithelial ion transport in the rat late distal colon by the sympathetic nervous system.

X Zhang et al.

Physiological research, 64(1), 103-110 (2014-09-07)

The colorectum (late distal colon) is innervated by the sympathetic nervous system, and many colorectal diseases are related to disorders of the sympathetic nervous system. The sympathetic regulation of colorectal ion transport is rarely reported. The present study aims to

Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons.

Michael Y Aksenov et al.

Neurotoxicology, 29(6), 971-977 (2008-07-09)

Drug abuse is a risk factor for neurological complications in HIV infection. Cocaine has been shown to exacerbate HIV-associated brain pathology and enhance neurotoxicity of HIV-1 Tat and gp120 proteins. In this study, we found that the selective inhibitor of

Cardiac sympathetic innervation and PGP9.5 expression by cardiomyocytes after myocardial infarction: effects of central MR blockade.

Anastasia Drobysheva et al.

American journal of physiology. Heart and circulatory physiology, 305(12), H1817-H1829 (2013-10-15)

Central mechanisms involving mineralocorticoid receptor (MR) activation contribute to an increase in sympathetic tone after myocardial infarction (MI). We hypothesized that this central mechanism also contributes to cardiac sympathetic axonal sprouting and that central MR blockade reduces cardiac sympathetic hyperinnervation

Differences in chemo- and cytoarchitectural features within pars principalis of the rat anterior olfactory nucleus suggest functional specialization.

Elizabeth Amory Meyer et al.

The Journal of comparative neurology, 498(6), 786-795 (2006-08-24)

The anterior olfactory nucleus (AON) lies between the olfactory bulb and piriform cortex and is the first bilaterally innervated structure in the olfactory system. It is typically divided into two subregions: pars externa and pars principalis. We examined the cytoarchitecture

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